Source: http://rss.cnn.com/~r/rss/cnn_health/~3/cLj9Lg3uLPo/index.html
Wednesday, May 30, 2012
Is there a bias against creativity?
Creativity has taken center stage in recent years, with a slew of books, articles and TED talks extolling the virtues of imagination and exhorting young and old to go out and exercise their creative muscle. 
Information on the new procedure "Calf Implants" is now available at PlasticSurgery.com
A new procedure is now available on PlasticSurgery.com. Visit PlasticSurgery now to learn all about it!
Source: http://www.plasticsurgery.com/procedure-Calf_Implants/procedure/info.html
Information on the new procedure "Threadlift" is now available at PlasticSurgery.com
A new procedure is now available on PlasticSurgery.com. Visit PlasticSurgery now to learn all about it!
Source: http://www.plasticsurgery.com/procedure-Threadlift/procedure/info.html
Nuts: Portion control is key
Nuts pack a powerful punch as a snack, but portion control is key. Susan Hendricks has more in today's Health Minute. 
Source: http://rss.cnn.com/~r/rss/cnn_health/~3/wKxPAt7OLQ8/
The Fate of Adipocytes after Nonvascularized Fat Grafting: Evidence of Early Death and Replacement of Adipocytes
Background: Clinical outcomes following fat grafting are variable and technique dependent, and it is unknown how the graft is revascularized. The authors recently observed that living and dead adipocytes can be differentiated not with hematoxylin and eosin staining but with immunohistochemistry for perilipin.
Methods: The viability of cellular components (adipocytes, adipose stem/stromal/progenitor cells, vascular endothelial cells, and hematopoietic cells) in human adipose tissue was evaluated using (1) stored lipoaspirates, (2) cultured cells, and (3) organ-cultured adipose tissue. In addition, the groin fat pad (150 to 200 mg) in mice was transplanted under the scalp, and the graft was stained at 0, 1, 2, 3, 5, 7, or 14 days.
Results: In vitro studies revealed that adipocytes are most susceptible to death under ischemic conditions, although adipose-derived stromal cells can remain viable for 3 days. The in vivo study indicated that most adipocytes in the graft began to die on day 1, and only some of the adipocytes located within 300 ?m of the tissue edge survived. The number of proliferating cells increased from day 3, and an increase in viable adipocyte area was detected from day 7, suggesting that repair/regeneration of the dead tissue had begun.
Conclusions: The authors show convincing evidence of very dynamic remodeling of adipose tissue after nonvascularized grafting. The authors observed three zones from the periphery to the center of the graft: the surviving area (adipocytes survived), the regenerating area (adipocytes died, adipose-derived stromal cells survived, and dead adipocytes were replaced with new ones), and the necrotic area (both adipocytes and adipose-derived stromal cells died).
Methods: The viability of cellular components (adipocytes, adipose stem/stromal/progenitor cells, vascular endothelial cells, and hematopoietic cells) in human adipose tissue was evaluated using (1) stored lipoaspirates, (2) cultured cells, and (3) organ-cultured adipose tissue. In addition, the groin fat pad (150 to 200 mg) in mice was transplanted under the scalp, and the graft was stained at 0, 1, 2, 3, 5, 7, or 14 days.
Results: In vitro studies revealed that adipocytes are most susceptible to death under ischemic conditions, although adipose-derived stromal cells can remain viable for 3 days. The in vivo study indicated that most adipocytes in the graft began to die on day 1, and only some of the adipocytes located within 300 ?m of the tissue edge survived. The number of proliferating cells increased from day 3, and an increase in viable adipocyte area was detected from day 7, suggesting that repair/regeneration of the dead tissue had begun.
Conclusions: The authors show convincing evidence of very dynamic remodeling of adipose tissue after nonvascularized grafting. The authors observed three zones from the periphery to the center of the graft: the surviving area (adipocytes survived), the regenerating area (adipocytes died, adipose-derived stromal cells survived, and dead adipocytes were replaced with new ones), and the necrotic area (both adipocytes and adipose-derived stromal cells died).
Information on the new procedure "Chin Augmentation" is now available at PlasticSurgery.com
A new procedure is now available on PlasticSurgery.com. Visit PlasticSurgery now to learn all about it!
Source: http://www.plasticsurgery.com/procedure-Chin_Augmentation/procedure/info.html
Single-Stage Breast Reconstruction with the Anterior Approach Latissimus Dorsi Flap and Permanent Implants
Background: Traditional latissimus dorsi myocutaneous flap breast reconstruction results in a large wound on the back, difficult inset of flap, and skin color disparity. An anterior approach to harvesting the latissimus dorsi muscle flap reduces morbidity, and with skin-sparing mastectomy, immediate single-stage reconstruction with a permanent implant is provided.
Methods: A retrospective review was performed of patients who underwent skin-sparing mastectomies and immediate reconstruction with the anterior approach latissimus dorsi muscle flap and permanent implant with 6- to 12-month follow-up. All procedures were performed by a single surgeon at three facilities from January of 2008 through December of 2008. Data included the patient's age; body mass index; history of axillary dissection, chemotherapy, or irradiation; occurrence of seroma, flap necrosis, infection, or cellulitis; and the need for further surgery.
Results: Fifty-eight reconstructions were performed in 36 patients (bilateral, 22 patients). Major complications included pulmonary embolism in one patient, removal of both implants in one patient because of infection, and removal of one implant because of hematoma. Minor complications included seroma in 40 of 58 procedures (68.9 percent), flap necrosis in seven (12 percent), cellulitis in four (6.8 percent), and a secondary procedure for cosmesis in four (6.8 percent). Seroma formation was more frequent in patients with a body mass index greater than 25 kg/m2, patients aged older than 50 years, and after axillary dissection (p > 0.05).
Conclusions: The anterior approach latissimus dorsi muscle flap with permanent implants provides a single-stage reconstructive option after skin-sparing mastectomy. Postoperative morbidity is comparable to that of the traditional latissimus dorsi muscle flap.
CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, IV.
Methods: A retrospective review was performed of patients who underwent skin-sparing mastectomies and immediate reconstruction with the anterior approach latissimus dorsi muscle flap and permanent implant with 6- to 12-month follow-up. All procedures were performed by a single surgeon at three facilities from January of 2008 through December of 2008. Data included the patient's age; body mass index; history of axillary dissection, chemotherapy, or irradiation; occurrence of seroma, flap necrosis, infection, or cellulitis; and the need for further surgery.
Results: Fifty-eight reconstructions were performed in 36 patients (bilateral, 22 patients). Major complications included pulmonary embolism in one patient, removal of both implants in one patient because of infection, and removal of one implant because of hematoma. Minor complications included seroma in 40 of 58 procedures (68.9 percent), flap necrosis in seven (12 percent), cellulitis in four (6.8 percent), and a secondary procedure for cosmesis in four (6.8 percent). Seroma formation was more frequent in patients with a body mass index greater than 25 kg/m2, patients aged older than 50 years, and after axillary dissection (p > 0.05).
Conclusions: The anterior approach latissimus dorsi muscle flap with permanent implants provides a single-stage reconstructive option after skin-sparing mastectomy. Postoperative morbidity is comparable to that of the traditional latissimus dorsi muscle flap.
CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, IV.
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